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  Yang Qi-En
Yang Qi-En
   Associate Director
   23 Xinning Rd, Xining, Qinghai Province
Zip Code  

Education and Appointments:

Dr.Qi-En Yang is a principal investigator at the Northwest Institute of Plateau Biology, the Chinese Academy of Sciences. Yang earned a bachelor's degree in Animal Science and a master's degree in Animal Genetics and Reproductive Biology from the China Agricultural University in 2004 and 2006. He obtained his Ph.D. from the University of Florida in 2010. Yang spent 3 years at the Washington State University as a Lalor Foundation postdoctoral fellow and later as a research assistant professor. In 2015, he was recruited to "100 Talents Recruitment Plan" at the Northwest Institute of Plateau Biology. Dr. Yang's lab uses genetically engineered mouse models and large animals to study molecular regulation of stem cell fate decisions and reproductive isolation in mammals. His work has been published in prestigious journals including Nature Communications, Cell Reports, Development, PLoS Genetics, Stem Cell Reports, Journal of Cell Science, Biology of Reproduction.

Research Interest:

Reproductive Biology, Functional Genomics

Public Services:


2012  Lalor Foundation Postdoctoral Fellowship, the Lalor Foundation 
2012 Lalor Foundation Merit Award, Society for the Study of Reproduction 

Seleted Publication:

1. Jia GX, Ma WJ, Wu ZB, Li S, Zhang XQ, He Z, Wu SX, Tao HP, Fang Y, Song YW, Xu SR, Wang XQ*, Yang QE*. Single-cell transcriptomic characterization of sheep conceptus elongation and implantation.
Cell Rep. 2023;42(8):112860.
2. Tao HP, Lu TF, Li S, Jia GX, Zhang XN, Yang QE*, Hou YP*. Pancreatic lipase-related protein 2 is selectively expressed by peritubular myoid cells in the murine testis and sustains long-term spermatogenesis. Cellular and Molecular Life Sciences 2023;80(8):217.
3. Gao X, Wang S, Wang YF, Li  S, Wu SX, Yan RG, Zhang YW, Wan RD, He Z, Song RD, Zhao XQ*, Wu DD*, Yang QE*. Long read genome assemblies complemented by single cell RNA-sequencing reveal genetic and cellular mechanisms underlying the adaptive evolution of Yak.  Nature Communications, 2022;13(1): 4887.
4. Jia GX, Lin Z, Yan RG, Wang GW, Zhang XN, Li C, Tong MH, Yang QE*.  Wtap function in Sertoli cells is essential for sustaining spermatogonial stem cell niche. Stem Cell Reports, 2020;15(4):968-982.
5. Wang GW, Li YC,Yang QL, Xu SR, Ma SK, Yan RG, Zhang RN, Jia GX, Ai DQ, Yang QE*. Gene expression dynamics during the gonocyte to spermatogonia transition and spermatogenesis in the domestic yak. Journal of Animal Science & Biotechnology, 2019;10:64.

Supported Projects:

National Key Research and Development Project, National Natural Science Foundation of China, Qinghai Science and Technology Department Major Project