实验室介绍
魏立新 研究员

学历:博士研究生

学科:藏医药

电话:0971-6143668

邮箱:lxwei@nwipb.cas.cn

地址:青海省西宁市城西区新宁路23号

邮编:810008

简历介绍

魏立新,男,1967年10月生于山西盂县,1991年毕业于中国农业大学生命科学学院,获理学学士学位。2001年获中国科学院研究生院理学博士学位。2004年在德国马普学会生态化学研究所从事访问研究,2010年1月至2011年1月在美国纽约大学药理系做高级访问学者。现任国家药典委员会委员,世界中医药联合会自然疗法专业委员会常务理事,中国民族医药学会常务理事,中国民族医药协会常务理事,青海省藏药药理学与安全性评价研究重点实验室主任,青海省药学会副理事长,青海省药学会中藏药与天然药物专业委员会主任,《世界科学技术—中医药现代化》和《中国中药杂志》编委。

主要从事藏药领域研究,主持制定藏药技术标准70项,其中包括国药准字号药品标准22项,《中国药典》药材标准1项;发表研究论文70余篇,出版专著1部;申请发明专利16项,其中授权6项;鉴定科技成果12项,其中国际领先2项。培养研究生33名,其中硕士26名,博士7名,培养中组部中科院“西部之光”人才2名。2011年获中国科学院王宽诚西部学者突出贡献奖;2011年获得中国科学院“西部之光”优秀学者称号;2012年获得国务院政府特殊津贴。

主持项目情况:2003年以来主持项目20项,总经费约7600万元,其中国家级项目12项,主要包括“十二五”国家科技支撑计划重点项目“民族医特色疗法疗效评价及平台技术研究”,2012至2014年,经费3379万元;国家自然科学基金面上项目“藏药佐太中汞在肠壁跨膜转运中的价态、配位形式及分子行为机制研究”,2014-2017年,经费62万;“十一五”国家科技支撑计划重点项目“民族医药发展关键技术示范研究”,2007至2011年,经费2914万;国家重大科技专项“重大新药创制”课题“藏药君西区域炮制规范示范研究”;国家药典委员会项目“六种藏药材质量标准研究”;科技部专项“国家民族医药发展战略研究”;国家科技支撑计划课题“桑蒂苷胶囊新药研究”;科技部重大基础研究前期专项“药用明胶胶囊对凝血系统影响研究”等。 

研究方向

现主要从事藏药药理与毒理研究,特别是含重金属传统药物的安全性和有效性评价。

职务
副所长
社会任职
国家药典委员会委员中国民族医药协会常务理事
获奖及荣誉

 2007-2009, 6 patent applications accepted by State Intellectual Property Office
2006, 2007 and 2008, Granted by the Ministry of Science & Technology of the People’s Republic of China (MOST)
2001, 2003 and 2005, Granted by Chinese Academy of Sciences (CAS), China
2004, Chinese Academy of Sciences Scholarship
2004, Granted by Qinghai Science & Technology Department, China
2000, State Key Laboratory of Bio-Organic and Natural Products Chemistry Fellowship
Member of Chinese Pharmacopoeia Commission
Executive director of China Association of Minority Medicine
Reviewer of National Natural Science Foundation of China
Senior member of Chinese Pharmaceutical Association
Member of Youth Association of the Chinese Academy of Sciences
Oral presentator of ICMTCM 2002 and 67th International Congress of FIP 2007

代表论文

HAN Qing, WEI Li-xin, DU Yu-zhi. The Effects of Extract from Tibetan Medicine Swertia mussotii Franch on Hydroxyproline in Rat Liver Fibrosis made by CCl4. Chinese Traditional Patent Medicine, 2009 (in press)

CHEN Xian-min, WEI Li-xin, DU Yu-zhi, WANG Ping-ping. The Current Research Progress on Pharmacological Effects of Cinnabar on Brain and Nervous System. Journal of Anhui Agricultural Sciences. 2009, 37 (8): 3372-3373, 3375

WANG Ping-ping, CHEN Xian-min, XIAO Yuan-can, DU Yu-zhi, WEI Li-xin. Studies on Chemical Constituents from the Tibetan Materia Medica Swertia chirata Extracted with Petrolelum Ether. Journal of Anhui Agricultural Sciences. 2009, 37 (4): 1625-1626

WEI Li-xin, DU Yu-zhi, ZOU Xiao-yan, XIAO Yuan-can. Determination of Piperine in Tibetan Medicine PAZHU Capsule by HPLC. Chinese Traditional Patent Medicine, 2008, 30 (3): 454-455

WEI Li-xin, DU Yu-zhi. Chemical Components Analysis by GC-MS of Supercritical-CO2 Extracts from Tibetan Medicine PAZHU Capsule. Chinese Traditional Patent Medicine, 2008, 30 (2): 236-238

Peng Y S, Brown M A, Wu J P, Wei Li-xin, Wu J L, Sanbei D Z. Fatty Acid Profile in Milk Fat from Qinghai Plateau Yak at Different Altitudes and Parities1. Professional Animal Scientist, 2008

ZOU Xiao-yan, WEI Li-xin, DU Yu-zhi, GUO Son-chang, HAN Qing, XIAO Yuan-can. Optimum extracting process for Swertia mussotii F. by central composite design/response surface method. Chinese Traditional and Herbal Drugs, 2008, 39 (5): 692-696

ZOU Xiao-yan, WEI Li-xin, DU Yu-zhi, HAN Qing, Zhao Xu-dong. Optimum Extracting Technology of Swertia Mussotii F. with Orthogonal Test. Journal of Anhui Agricultural Sciences. 2008, 36 (3): 851-852

HAN Qing, WEI Li-xin, DU Yu-zhi, ZOU Xiao-yan. The Study of Extract from Tibetan Medicine Swertia mussotii Franch on Anti-Fibrosis in Rat Liver made by CCl4. Pharmacology and Clinics of Chinese Materia Medica, 2008, 24 (5): 34-36

WEI Li-xin, DU Yu-zhi. Determination of Fatty Acids and Total Lipid Content in Oilseed of Pomegrantate (used as Tibetan Materia Medica) by GC-MS of Supercritical-CO2 Extracts. Journal of Chinese Medicinal Materials. 2007, 30 (11): 1401-1403

Wang L, Xiao H B, Liang X M, Wei Li-xin. Identification of Phenolics and Nucleoside Derivatives in Gastrodia elata by HPLC-UV-MS. Journal of Separation of Science. 2007, 30: 1488-1495

JIN You-cai, XIAO Yuan-can, ZOU Xiao-yan, L  Ping, DU Yu-zhi, WEI Li-xin. Determination of Four Glycoside Constituents in Two kinds of Tibetan Materia Medica Swertia by HPLC. Journal of Anhui Agricultural Sciences. 2007, 35 (7): 1889-1890

L  Ping, WEI Li-xin, DU Yu-zhi, WAN An-zhu, LI Guo-qing. Technology of Preparing Food-grade Gelatin by Alkaline Protease Hydrolyzing Bone Collagen. Journal of Anhui Agricultral Sciences. 2007, 35 (27): 6235, 6239

DU Yu-zhi, WEI Li-xin, L  Ping, XIAO Yuan-can. Study on Elements of Mineral and Heavy Metals in Tibetan Medicine PAZHU Capsule. Guangdong Trace Elements Science, 2007, 14 (4): 32-35

WEI Li-xin. The Medicinal Plant Swertia chirata Originating in India was Cultivated Successfully on Qinghai-Tibet Plateau. Science Technology Innovations and Brands, 2007,6:20-21

QU Jin, WEI Li-xin. The Research Advances on Potential Risk of Pharmaceutical Gelatin in Coagulation Function. Chinese Journal of Public Health, 2006, 22 (5): 622-623

L  Ping, DU Yu-zhi, WEI Li-xin. The Research Advances of Gelatin Preparation with Enzymolysis. The Science and Technology of Gelatin, 26 (4): 170-176

QU Jin, WEI Li-xin, DU Yu-zhi, HAI Ping, LIANG Xia, XUE Hong. Labeling of Gelatin with 99Tcm and it’s Biodistribution. Journal of Nuclear and Radiochemistry, 2006, 28 (4): 244-248

WEI Li-xin, ZHANG Bao-chen, DU Yu-zhi. The Analysis of Hydroxyproline in Sailongu and Hugu Bone. Amino Acids and Biotic Resources, 2001, 23 (3): 9-12

WEI Li-xin, ZHANG Bao-chen, TAO Yan-duo, DU Yu-zhi. Studies on Quality Control of XUELONG Capsule. Chinese Traditional and Herbal Drugs, 2001, 32 (6): 510-511

WEI Li-xin, ZHANG Bao-chen. The Research Advances on Platelet Receptor for Collagen and it’s Antagonists. Foreign Medical Sciences (Section of Clinical Biochemistry and Laboratory Medicine, 2001, 22 (5): 271-273

WEI Li-xin,ZHANG Bao-chen. The Research Advances on interaction between vWF and Platelet and Collagen. Foreign Medical Sciences (Section of Clinical Biochemistry and Laboratory Medicine). 2001, 22 (Sup.): 27-29

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